Forced G1-phase reduction alters mode of division, neuron number, and laminar phenotype in the cerebral cortex

The link between cortical precursors G1 duration (TG1) and their mode of division remains a major unresolved issue of potential importance for regulating corticogenesis. Here, we induced a 25% reduction in TG1 in mouse cortical precursors via forced expression of cyclin D1 and cyclin E1. We found th...

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Detalhes bibliográficos
Main Authors: Pilaz, Louis-Jan, Patti, Dorothée, Marcy, Guillaume, Ollier, Edouard, Pfister, Sabina, Douglas, Rodney J., Betizeau, Marion, Gautier, Elodie, Cortay, Veronique, Doerflinger, Nathalie, Kennedy, Henry, Dehay, Colette
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788480/
https://ncbi.nlm.nih.gov/pubmed/19959663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909894106
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