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Molecular Basis for Bcl-2 Homology 3 Domain Recognition in the Bcl-2 Protein Family: IDENTIFICATION OF CONSERVED HOT SPOT INTERACTIONS

The proteins of the Bcl-2 family are important regulators of apoptosis, or programmed cell death. These proteins regulate this fundamental biological process via the formation of heterodimers involving both pro- and anti-apoptotic family members. Disruption of the balance between anti- and pro-apopt...

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Main Authors: Moroy, Gautier, Martin, Elyette, Dejaegere, Annick, Stote, Roland H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788401/
https://ncbi.nlm.nih.gov/pubmed/19293158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805542200
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