The Drosophila DHR96 nuclear receptor binds cholesterol and regulates cholesterol homeostasis

Cholesterol homeostasis is required to maintain normal cellular function and avoid the deleterious effects of hypercholesterolemia. Here we show that the Drosophila DHR96 nuclear receptor binds cholesterol and is required for the coordinate transcriptional response of genes that are regulated by cho...

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Bibliografski detalji
Glavni autori: Horner, Michael A., Pardee, Keith, Liu, Suya, King-Jones, Kirst, Lajoie, Gilles, Edwards, Aled, Krause, Henry M., Thummel, Carl S.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2009
Teme:
Research Communication
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788327/
https://ncbi.nlm.nih.gov/pubmed/19952106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1833609
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