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Stu1 inversely regulates kinetochore capture and spindle stability

The Saccharomyces cerevisiae CLASP (CLIP-associated protein) Stu1 is essential for the establishment and maintenance of the mitotic spindle. Furthermore, Stu1 localizes to kinetochores. Here we show that, in prometaphase, Stu1 assembles in an Ndc80-dependent manner exclusively at kinetochores that a...

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Detalhes bibliográficos
Main Authors: Ortiz, Jennifer, Funk, Caroline, Schäfer, Astrid, Lechner, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788326/
https://ncbi.nlm.nih.gov/pubmed/19952112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.541309
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