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The state of the art: immune-mediated mechanisms of monoclonal antibodies in cancer therapy

A number of antibody products have now become accepted as effective anti-cancer therapies. Despite being mainly designed to act by inhibiting functional tumour antigens, there is increasing evidence that Fc-mediated engagement of the immune system is an important contributor to the efficacy of sever...

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Detalhes bibliográficos
Main Authors: Griggs, J, Zinkewich-Peotti, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788263/
https://ncbi.nlm.nih.gov/pubmed/19809433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605349
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