Profiling of high-grade central osteosarcoma and its putative progenitor cells identifies tumourigenic pathways

BACKGROUND: Osteosarcoma is the most prevalent primary malignant bone tumour in children and young adults, with poor survival in 40% of patients. To identify the signalling pathways involved in tumourigenesis, we compared gene expression in osteosarcoma with that in its presumed normal counterparts....

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Detalhes bibliográficos
Main Authors: Cleton-Jansen, A-M, Anninga, J K, Briaire-de Bruijn, I H, Romeo, S, Oosting, J, Egeler, R M, Gelderblom, H, Taminiau, A H M, Hogendoorn, P C W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788255/
https://ncbi.nlm.nih.gov/pubmed/19888226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605405
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