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Beta-Catenin Nuclear Labeling is a Common Feature of Sessile Serrated Adenomas and Correlates with Early Neoplastic Progression Following BRAF Activation

Recent observations indicate that some sessile serrated adenomas (SSAs) have aberrant β-catenin nuclear labeling, implicating the Wnt pathway in the molecular progression of SSAs to colorectal carcinoma. We sought to expand upon this finding by characterizing β-catenin expression in the full spectru...

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Detalhes bibliográficos
Main Authors: Yachida, Shinichi, Mudali, Shiyama, Martin, Sherri A., Montgomery, Elizabeth A., Iacobuzio-Donahue, Christine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788075/
https://ncbi.nlm.nih.gov/pubmed/19745699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0b013e3181b6da19
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