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Long-term Suppression of GABAergic Activity by Neonatal Seizures in Rat Somatosensory Cortex

Here we studied the long-term effects of neonatal seizures on inhibitory synaptic transmission in somatosensory cortex. We found that recurrent flurothyl-induced seizures result in a marked reduction in amplitude of spontaneous inhibitory postsynaptic currents (IPSCs) and increases of miniature IPSC...

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Detalhes bibliográficos
Main Authors: Isaeva, Elena, Isaev, Dmytro, Khazipov, Rustem, Holmes, Gregory L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788005/
https://ncbi.nlm.nih.gov/pubmed/19828295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2009.09.011
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