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Identification of hydrophobic amino acids required for lipid activation of C. elegans CTP:phosphocholine cytidylyltransferase

CTP:phosphocholine cytidylyltransferase (CCT), critical for phosphatidylcholine biosynthesis, is activated by translocation to the membrane surface. The lipid activation region of Caenorhabditis elegans CCT is between residues 246 and 266 of the 347 amino acid polypeptide, a region proposed to form...

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Autors principals: Braker, Jay D, Hodel, Kevin J., Mullins, David R., Friesen, Jon A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787997/
https://ncbi.nlm.nih.gov/pubmed/19836342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.10.004
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