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Long Term Increased Expression of the Short Form 1b Prolactin Receptor in PC-3 Human Prostate Cancer Cells Decreases Cell Growth and Migration, and Causes Multiple Changes in Gene Expression Consistent with Reduced Invasive Capacity
BACKGROUND: We have shown that treatment of human prostate cancer cells with the selective prolactin (PRL) receptor modulator, S179D PRL, inhibits growth in vitro, and the initiation and growth of xenografts in vivo. S179D PRL treatment also upregulates expression of the short form 1b (SF1b) PRL rec...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787886/ https://ncbi.nlm.nih.gov/pubmed/19739126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21036 |
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