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A novel brain injury mechanism after intracerebral hemorrhage: the interaction between heme products and the immune system
In this paper we hypothesize a novel mechanism by which brain injury occurs after intracerebral hemorrhage. We propose the following mechanism: 1) heme derived from extravasated erythrocytes is degraded into bilirubin and bilirubin oxidation products (BOXes). 2) Bilirubin and BOXes activate microgli...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787807/ https://ncbi.nlm.nih.gov/pubmed/19716661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2009.08.002 |
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