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Free-solution Label-free Detection of α-crystallin Chaperone Interactions by Back-scattering Interferometry

We report the quantitative, label-free analysis of protein-protein interactions in free solution within picoliter volumes using backscatter interferometry (BSI). Changes in the refractive index are measured for solutions introduced on a PDMS microchip allowing determination of forward and reverse ra...

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Detalhes bibliográficos
Main Authors: Latham, Joey C., Stein, Richard, Bornhop, Darryl J., Mchaourab, Hassane S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787765/
https://ncbi.nlm.nih.gov/pubmed/19178288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac802327h
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