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Polk Mutant Mice Have a Spontaneous Mutator Phenotype
Mice defective in the Polk gene (which encodes DNA polymerase kappa) are viable and do not manifest obvious phenotypes. The present studies document a spontaneous mutator phenotype in Polk(−/−) mice. The initial indication of enhanced spontaneous mutations in these mice came from the serendipitous o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787749/ https://ncbi.nlm.nih.gov/pubmed/19783230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.09.003 |
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