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Sphingosine Kinase 1 Localized to the Plasma Membrane Lipid Raft Microdomain Overcomes Serum Deprivation Induced Growth Inhibition

Several studies have demonstrated that sphingosine kinase 1 (SphK1) translocates to the plasma membrane (PM) upon its activation and further suggested the plasma membrane lipid raft microdomain (PMLRM) as a target for SphK1 relocalization. To date, however, direct evidence of SphK1 localization to t...

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Detalhes bibliográficos
Main Authors: Hengst, Jeremy A., Francy-Guilford, Jacquelyn M., Fox, Todd E., Wang, Xujun, Conroy, Elizabeth J., Yun, Jong K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787747/
https://ncbi.nlm.nih.gov/pubmed/19782042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.09.013
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