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CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs
Drosha-processed microRNAs (miRNAs) have been shown to be exported from the nucleus to the cytoplasm by Exportin 5, where they are processed a second time to generate mature miRNAs. In this work we show that miRNAs also use CRM1 for nuclear-cytoplasmic shuttling. Inhibition of CRM1 by Leptomycin B r...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787469/ https://ncbi.nlm.nih.gov/pubmed/19955415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912384106 |
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