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A Problem With the Correlation Coefficient as a Measure of Gene Expression Divergence

The correlation coefficient is commonly used as a measure of the divergence of gene expression profiles between different species. Here we point out a potential problem with this statistic: if measurement error is large relative to the differences in expression, the correlation coefficient will tend...

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Библиографические подробности
Главные авторы: Pereira, Vini, Waxman, David, Eyre-Walker, Adam
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787443/
https://ncbi.nlm.nih.gov/pubmed/19822726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.110247
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