Heme Oxygenase-1 Inhibits Pro-Oxidant Induced Hypertrophy in HL-1 Cardiomyocytes

AIMS: Reactive oxygen species (ROS) activate multiple signaling pathways involved in cardiac hypertrophy. Since HO-1 exerts potent antioxidant effects, we hypothesized that this enzyme inhibits ROS-induced cardiomyocyte hypertrophy. METHODS: HL-1 cardiomyocytes were transduced with an adenovirus con...

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Bibliografiske detaljer
Main Authors: Brunt, Keith R., Tsuji, Matthew R., Lai, Joyce H., Kinobe, Robert T., Durante, William, Claycomb, William C., Ward, Christopher A., Melo, Luis G.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787409/
https://ncbi.nlm.nih.gov/pubmed/19244544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3181/0810-RM-312
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