Cation-independent Mannose 6-Phosphate Receptor: A COMPOSITE OF DISTINCT PHOSPHOMANNOSYL BINDING SITES

The 300-kDa cation-independent mannose 6-phosphate receptor (CI-MPR), which contains multiple mannose 6-phosphate (Man-6-P) binding sites that map to domains 3, 5, and 9 within its 15-domain extracytoplasmic region, functions as an efficient carrier of Man-6-P-containing lysosomal enzymes. To determ...

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Main Authors: Bohnsack, Richard N., Song, Xuezheng, Olson, Linda J., Kudo, Mariko, Gotschall, Russell R., Canfield, William M., Cummings, Richard D., Smith, David F., Dahms, Nancy M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Glycobiology and Extracellular Matrices
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787381/
https://ncbi.nlm.nih.gov/pubmed/19840944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056184
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