Heparin/Heparan Sulfate 6-O-Sulfatase from Flavobacterium heparinum: INTEGRATED STRUCTURAL AND BIOCHEMICAL INVESTIGATION OF ENZYME ACTIVE SITE AND SUBSTRATE SPECIFICITY

Heparin and heparan sulfate glycosaminoglycans (HSGAGs) comprise a chemically heterogeneous class of sulfated polysaccharides. The development of structure-activity relationships for this class of polysaccharides requires the identification and characterization of degrading enzymes with defined subs...

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Detalhes bibliográficos
Main Authors: Myette, James R., Soundararajan, Venkataramanan, Shriver, Zachary, Raman, Rahul, Sasisekharan, Ram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Enzyme Catalysis and Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787378/
https://ncbi.nlm.nih.gov/pubmed/19726671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053801
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