Identification and Characterization of Multiple Similar Ligand-binding Repeats in Filamin: IMPLICATION ON FILAMIN-MEDIATED RECEPTOR CLUSTERING AND CROSS-TALK

The actin-binding protein filamin links membrane receptors to the underlying cytoskeleton. The cytoplasmic domains of these membrane receptors have been shown to bind to various filamin immunoglobulin repeats. Notably, among 24 human filamin repeats, repeat 17 was reported to specifically bind to pl...

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Main Authors: Ithychanda, Sujay Subbayya, Hsu, Dennis, Li, Hanhan, Yan, Linda, Liu, Darwen, Das, Mitali, Plow, Edward F., Qin, Jun
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Biomolecular Networks
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787372/
https://ncbi.nlm.nih.gov/pubmed/19828450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.060954
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