Regulation of Homotypic Cell-Cell Adhesion by Branched N-Glycosylation of N-cadherin Extracellular EC2 and EC3 Domains

The effects of altering N-cadherin N-glycosylation on several cadherin-mediated cellular behaviors were investigated using small interfering RNA and site-directed mutagenesis. In HT1080 fibrosarcoma cells, small interfering RNA-directed knockdown of N-acetylglucosaminyltransferase V (GnT-V), a glyco...

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Bibliografiske detaljer
Main Authors: Guo, Hua-Bei, Johnson, Heather, Randolph, Matthew, Pierce, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787361/
https://ncbi.nlm.nih.gov/pubmed/19846557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.060806
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