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Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis

INTRODUCTION: Accumulation of B cells in the rheumatoid arthritis (RA) synovium has been reported, and it has been thought that these cells might contribute to the pathogenesis of RA by antigen presentation, autoantibody production, and/or inflammatory cytokine production. Chemokines could enhance t...

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Autors principals: Nanki, Toshihiro, Takada, Kazuki, Komano, Yukiko, Morio, Tomohiro, Kanegane, Hirokazu, Nakajima, Atsuo, Lipsky, Peter E, Miyasaka, Nobuyuki
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787286/
https://ncbi.nlm.nih.gov/pubmed/19804625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2823
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