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Fusion of epithelial cells by Epstein–Barr virus proteins is triggered by binding of viral glycoproteins gHgL to integrins αvβ6 or αvβ8

Epstein–Barr(,) virus (EBV) is a ubiquitous human herpesvirus that is causally implicated in the development of lymphoid and epithelial tumors. Entry of virus requires fusion of virus envelopes and cell membranes. Fusion with B lymphocytes requires virus glycoprotein gB and a 3-part complex of glyco...

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Библиографические подробности
Главные авторы: Chesnokova, Liudmila S., Nishimura, Stephen L., Hutt-Fletcher, Lindsey M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787161/
https://ncbi.nlm.nih.gov/pubmed/19920174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907508106
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