Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling

Systemic lupus erythematosus (SLE) is a complex autoimmune disease affecting various tissues. Involvement of B and T cells as well as increased cytokine levels have been associated with disease manifestation. Recently, we demonstrated that mice with epidermal loss of JunB (JunB(Δep)) develop a myelo...

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Detalhes bibliográficos
Main Authors: Pflegerl, Pamina, Vesely, Paul, Hantusch, Brigitte, Schlederer, Michaela, Zenz, Rainer, Janig, Elke, Steiner, Günter, Meixner, Arabella, Petzelbauer, Peter, Wolf, Peter, Soleiman, Afschin, Egger, Gerda, Moriggl, Richard, Kishimoto, Tadamitsu, Wagner, Erwin F., Kenner, Lukas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787143/
https://ncbi.nlm.nih.gov/pubmed/19918056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910371106
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