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Cdk5-Dependent Regulation of Rho Activity, Cytoskeletal Contraction, and Epithelial Cell Migration via Suppression of Src and p190RhoGAP

Cdk5 regulates adhesion and migration in a variety of cell types. We previously showed that Cdk5 is strongly activated during stress fiber formation and contraction in spreading cells. Here we determine the mechanism linking Cdk5 to stress fiber contractility and its relevance to cell migration. Imm...

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Bibliografski detalji
Glavni autori: Tripathi, Brajendra K., Zelenka, Peggy S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786874/
https://ncbi.nlm.nih.gov/pubmed/19822667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01098-09
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