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Heparan Sulfate Proteoglycans Are Required for Cellular Binding of the Hepatitis E Virus ORF2 Capsid Protein and for Viral Infection

The hepatitis E virus (HEV), a nonenveloped RNA virus, is the causative agent of hepatitis E. The mode by which HEV attaches to and enters into target cells for productive infection remains unidentified. Open reading frame 2 (ORF2) of HEV encodes its major capsid protein, pORF2, which is likely to h...

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Detalhes bibliográficos
Main Authors: Kalia, Manjula, Chandra, Vivek, Rahman, Sheikh Abdul, Sehgal, Deepak, Jameel, Shahid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786843/
https://ncbi.nlm.nih.gov/pubmed/19812150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00717-09
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