Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

Natural SIV infection of sooty mangabeys (SMs) is nonprogressive despite chronic virus replication. Strikingly, it is characterized by low levels of immune activation, while pathogenic SIV infection of rhesus macaques (RMs) is associated with chronic immune activation. To elucidate the mechanisms un...

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Detalhes bibliográficos
Main Authors: Bosinger, Steven E., Li, Qingsheng, Gordon, Shari N., Klatt, Nichole R., Duan, Lijie, Xu, Luoling, Francella, Nicholas, Sidahmed, Abubaker, Smith, Anthony J., Cramer, Elizabeth M., Zeng, Ming, Masopust, David, Carlis, John V., Ran, Longsi, Vanderford, Thomas H., Paiardini, Mirko, Isett, R. Benjamin, Baldwin, Don A., Else, James G., Staprans, Silvija I., Silvestri, Guido, Haase, Ashley T., Kelvin, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786806/
https://ncbi.nlm.nih.gov/pubmed/19959874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40115
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