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Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-α expression

Cutaneous wounds heal more slowly in elderly males than in elderly females, suggesting a role for sex hormones in the healing process. Indeed, androgen/androgen receptor (AR) signaling has been shown to inhibit cutaneous wound healing. AR is expressed in several cell types in healing skin, including...

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Detalhes bibliográficos
Main Authors: Lai, Jiann-Jyh, Lai, Kuo-Pao, Chuang, Kuang-Hsiang, Chang, Philip, Yu, I-Chen, Lin, Wen-Jye, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786793/
https://ncbi.nlm.nih.gov/pubmed/19907077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39335
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