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Distinct Regulation of Hepatitis B Virus Biosynthesis by Peroxisome Proliferator-Activated Receptor γ Coactivator 1α and Small Heterodimer Partner in Human Hepatoma Cell Lines

The human hepatoma cell lines HepG2 and Huh7 have been used extensively to study hepatitis B virus (HBV) transcription and replication. Both cell lines support transcription of the 3.5-kb viral pregenomic RNA and subsequent viral DNA synthesis by reverse transcription. The effects of the coactivator...

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Autori principali: Ondracek, Caitlin R., Reese, Vanessa C., Rushing, Christel N., Oropeza, Claudia E., McLachlan, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786761/
https://ncbi.nlm.nih.gov/pubmed/19793803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01624-09
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