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A Single Point Mutation in Nonstructural Protein NS2 of Bovine Viral Diarrhea Virus Results in Temperature-Sensitive Attenuation of Viral Cytopathogenicity

For Bovine viral diarrhea virus (BVDV), the type species of the genus Pestivirus in the family Flaviviridae, cytopathogenic (cp) and noncytopathogenic (ncp) viruses are distinguished according to their effect on cultured cells. It has been established that cytopathogenicity of BVDV correlates with e...

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Autores principales: Pankraz, Alexander, Preis, Simone, Thiel, Heinz-Jürgen, Gallei, Andreas, Becher, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786742/
https://ncbi.nlm.nih.gov/pubmed/19776121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01487-09
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