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Insertion of Enhanced Green Fluorescent Protein in a Hinge Region of Vesicular Stomatitis Virus L Polymerase Protein Creates a Temperature-Sensitive Virus That Displays No Virion-Associated Polymerase Activity In Vitro
The RNA-dependent RNA polymerase of viruses belonging to the order Mononegavirales is part of a large multifunctional L protein that also catalyzes viral mRNA capping and cap methylation. The L protein of this diverse group of agents displays six blocks of conserved sequences. The precise relationsh...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786726/ https://ncbi.nlm.nih.gov/pubmed/19793815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01273-09 |
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