Clinical Performance of Human Papillomavirus E6 and E7 mRNA Testing for High-Grade Lesions of the Cervix

Infection with high-risk (HR) human papillomavirus (HPV) is the major cause of cervical cancer. However, relatively few infections progress to malignant disease. Progression to malignancy requires the overexpression of the E6 and E7 genes in the integrated HPV genome. It follows that the E6 and E7 t...

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Bibliographische Detailangaben
Hauptverfasser: Cattani, Paola, Zannoni, Gian Franco, Ricci, Caterina, D'Onghia, Sara, Trivellizzi, Ilaria Nausica, Di Franco, Aldo, Vellone, Valerio G., Durante, Maria, Fadda, Giovanni, Scambia, Giovanni, Capelli, Giovanni, De Vincenzo, Rosa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Virology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786669/
https://ncbi.nlm.nih.gov/pubmed/19828739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01275-09
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