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Determination of Echinocandin MICs for Candida Species in Less than 8 Hours: Comparison of the Rapid Susceptibility Assay with the Clinical and Laboratory Standards Institute's Broth Microdilution Assay

The echinocandins prevent fungal cell wall synthesis by inhibiting β-1,3-glucan synthesis, a significant glucose-consuming process. Previous studies suggested that echinocandin inhibitory activity is evident within 1 h of exposure. We hypothesized that a susceptibility assay based on glucose consump...

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Detalhes bibliográficos
Main Authors: Hazen, Kevin C., Dirks, Dawn, Masuoka, James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786658/
https://ncbi.nlm.nih.gov/pubmed/19846655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01306-09
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