Evaluation of Hepatitis C Virus Core Antigen Assays in Detecting Recombinant Viral Antigens of Various Genotypes

A single substitution within the hepatitis C virus core antigen sequence, A48T, which is observed in ∼30% of individuals infected with genotype 2a virus, reduces the sensitivity of a commonly used chemiluminescence enzyme immunoassay. Quantitation of the antigen is improved by using a distinct antic...

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Bibliografiske detaljer
Main Authors: Saeed, Mohsan, Suzuki, Ryosuke, Kondo, Madoka, Aizaki, Hideki, Kato, Takanobu, Mizuochi, Toshiaki, Wakita, Takaji, Watanabe, Haruo, Suzuki, Tetsuro
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Virology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786616/
https://ncbi.nlm.nih.gov/pubmed/19812276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01437-09
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