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Cag3 Is a Novel Essential Component of the Helicobacter pylori Cag Type IV Secretion System Outer Membrane Subcomplex

Helicobacter pylori strains harboring the cag pathogenicity island (PAI) have been associated with more severe gastric disease in infected humans. The cag PAI encodes a type IV secretion (T4S) system required for CagA translocation into host cells as well as induction of proinflammatory cytokines, s...

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Bibliographic Details
Main Authors: Pinto-Santini, Delia M., Salama, Nina R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786551/
https://ncbi.nlm.nih.gov/pubmed/19801411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00946-09
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