Pyruvate Formate Lyase Is Required for Pneumococcal Fermentative Metabolism and Virulence

Knowledge of the in vivo physiology and metabolism of Streptococcus pneumoniae is limited, even though pneumococci rely on efficient acquisition and metabolism of the host nutrients for growth and survival. Because the nutrient-limited, hypoxic host tissues favor mixed-acid fermentation, we studied...

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Detalhes bibliográficos
Main Authors: Yesilkaya, Hasan, Spissu, Francesca, Carvalho, Sandra M., Terra, Vanessa S., Homer, Karen A., Benisty, Rachel, Porat, Nurith, Neves, Ana R., Andrew, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786486/
https://ncbi.nlm.nih.gov/pubmed/19752030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00178-09
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