Pyruvate Formate Lyase Is Required for Pneumococcal Fermentative Metabolism and Virulence

Knowledge of the in vivo physiology and metabolism of Streptococcus pneumoniae is limited, even though pneumococci rely on efficient acquisition and metabolism of the host nutrients for growth and survival. Because the nutrient-limited, hypoxic host tissues favor mixed-acid fermentation, we studied...

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Main Authors: Yesilkaya, Hasan, Spissu, Francesca, Carvalho, Sandra M., Terra, Vanessa S., Homer, Karen A., Benisty, Rachel, Porat, Nurith, Neves, Ana R., Andrew, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786486/
https://ncbi.nlm.nih.gov/pubmed/19752030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00178-09
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