Toll-Like Receptors 2 and 4 Contribute to Sepsis-Induced Depletion of Spleen Dendritic Cells

Depletion of dendritic cells (DC) in secondary lymphoid organs is a hallmark of sepsis-induced immune dysfunction. In this setting, we investigated if Toll-like receptor (TLR)-dependent signaling might modulate the maturation process and the survival of DC. Using a model of sublethal polymicrobial s...

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Detalhes bibliográficos
Main Authors: Pène, Frédéric, Courtine, Emilie, Ouaaz, Fatah, Zuber, Benjamin, Sauneuf, Bertrand, Sirgo, Gonzalo, Rousseau, Christophe, Toubiana, Julie, Balloy, Viviane, Chignard, Michel, Mira, Jean-Paul, Chiche, Jean-Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786456/
https://ncbi.nlm.nih.gov/pubmed/19805530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00238-09
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