A Naturally Occurring Rgg Variant in Serotype M3 Streptococcus pyogenes Does Not Activate speB Expression Due to Altered Specificity of DNA Binding

The transcriptional regulator Rgg of Streptococcus pyogenes is essential for expression of the secreted cysteine protease SpeB. Although all isolates of S. pyogenes possess the speB gene, not all of them produce the protein in vitro. In a murine model of infection, the absence of SpeB production is...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Kappeler, Kyle V., Anbalagan, Srivishnupriya, Dmitriev, Alexander V., McDowell, Emily J., Neely, Melody N., Chaussee, Michael S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
主題:
Molecular Pathogenesis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786450/
https://ncbi.nlm.nih.gov/pubmed/19752034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00373-09
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍