Vaccination with the ML0276 Antigen Reduces Local Inflammation but Not Bacterial Burden during Experimental Mycobacterium leprae Infection

Leprosy elimination has been a goal of the WHO for the past 15 years. Widespread BCG vaccination and multidrug therapy have dramatically reduced worldwide leprosy prevalence, but new case detection rates have remained relatively constant. These data suggest that additional control strategies, such a...

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Autores principales: Raman, Vanitha S., O'Donnell, Joanne, Bailor, H. Remy, Goto, Wakako, Lahiri, Ramanuj, Gillis, Thomas P., Reed, Steven G., Duthie, Malcolm S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786448/
https://ncbi.nlm.nih.gov/pubmed/19786561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00508-09
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