Activity of the Novel Peptide Arminin against Multiresistant Human Pathogens Shows the Considerable Potential of Phylogenetically Ancient Organisms as Drug Sources

The emergence of multidrug-resistant bacteria highlights the need for new antibacterial agents. Arminin 1a is a novel antimicrobial peptide discovered during investigations of the epithelial defense of the ancient metazoan Hydra. Following proteolytic processing, the 31-amino-acid-long positively ch...

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Détails bibliographiques
Auteurs principaux: Augustin, René, Anton-Erxleben, Friederike, Jungnickel, Stephanie, Hemmrich, Georg, Spudy, Björn, Podschun, Rainer, Bosch, Thomas C. G.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Mechanisms of Action: Physiological Effects
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786370/
https://ncbi.nlm.nih.gov/pubmed/19770277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00826-09
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