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The Antituberculosis Drug Pyrazinamide Affects the Course of Cutaneous Leishmaniasis In Vivo and Increases Activation of Macrophages and Dendritic Cells

Antileishmanial therapy is suboptimal due to toxicity, high cost, and development of resistance to available drugs. Pyrazinamide (PZA) is a constituent of short-course tuberculosis chemotherapy. We investigated the effect of PZA on Leishmania major promastigote and amastigote survival. Promastigotes...

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Bibliografische gegevens
Hoofdauteurs: Mendez, Susana, Traslavina, Ryan, Hinchman, Meleana, Huang, Lu, Green, Patricia, Cynamon, Michael H., Welch, John T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786368/
https://ncbi.nlm.nih.gov/pubmed/19770283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01146-09
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