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In Vitro Sensitivity Testing of Leishmania Clinical Field Isolates: Preconditioning of Promastigotes Enhances Infectivity for Macrophage Host Cells

Diagnostic material from patients with leishmaniasis is generally available as promastigotes, and proper testing for susceptibility to first-line drugs by the intracellular amastigote assay is frequently hampered by the poor infectivity of the promastigotes for the macrophage host cell. Several cond...

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Bibliografiske detaljer
Main Authors: Inocêncio da Luz, Raquel, Vermeersch, Marieke, Dujardin, Jean-Claude, Cos, Paul, Maes, Louis
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786351/
https://ncbi.nlm.nih.gov/pubmed/19752271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00866-09
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