High Level of Cross-Resistance between Kanamycin, Amikacin, and Capreomycin among Mycobacterium tuberculosis Isolates from Georgia and a Close Relation with Mutations in the rrs Gene

The aminoglycosides kanamycin and amikacin and the macrocyclic peptide capreomycin are key drugs for the treatment of multidrug-resistant tuberculosis (MDR-TB). The increasing rates of resistance to these drugs and the possible cross-resistance between them are concerns for MDR-TB therapy. Mutations...

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Detalhes bibliográficos
Main Authors: Jugheli, Levan, Bzekalava, Nino, de Rijk, Pim, Fissette, Krista, Portaels, Françoise, Rigouts, Leen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786337/
https://ncbi.nlm.nih.gov/pubmed/19752274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00851-09
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