Fmt Bypass in Pseudomonas aeruginosa Causes Induction of MexXY Efflux Pump Expression

The intrinsic resistance of P. aeruginosa PAO1 to the peptide deformylase inhibitor (PDF-I) LBM415 was mediated by the MexAB-OprM and MexXY-OprM efflux pumps, the latter of which was strongly induced by LBM415. Single-step exposure of PAO1 deleted for mexAB-oprM (therefore lacking both MexAB-OprM an...

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Hlavní autoři: Caughlan, Ruth E., Sriram, Shubha, Daigle, Denis M., Woods, Angela L., Buco, Jennifer, Peterson, Ron L., Dzink-Fox, JoAnn, Walker, Susan, Dean, Charles R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786328/
https://ncbi.nlm.nih.gov/pubmed/19786597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00253-09
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