Genetic variation in the one carbon transfer pathway and ovarian cancer risk

Dysfunction in enzymes involved in one carbon (1-C) metabolism can lead to increased chromosomal strand breaking and abnormal methylation patterns; both are associated with cancer risk. Availability of 1-C units may modify risk. We investigated the association of single nucleotide polymorphisms (SNP...

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Huvudupphovsmän: Kelemen, Linda E, Sellers, Thomas A, Schildkraut, Joellen M, Cunningham, Julie M, Vierkant, Robert A, Pankratz, V Shane, Fredericksen, Zachary S, Gadre, Madhura K, Rider, David N, Liebow, Mark, Goode, Ellen L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786310/
https://ncbi.nlm.nih.gov/pubmed/18381459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5165
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