Genetic variation in the one carbon transfer pathway and ovarian cancer risk

Dysfunction in enzymes involved in one carbon (1-C) metabolism can lead to increased chromosomal strand breaking and abnormal methylation patterns; both are associated with cancer risk. Availability of 1-C units may modify risk. We investigated the association of single nucleotide polymorphisms (SNP...

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Bibliographic Details
Main Authors:	Kelemen, Linda E, Sellers, Thomas A, Schildkraut, Joellen M, Cunningham, Julie M, Vierkant, Robert A, Pankratz, V Shane, Fredericksen, Zachary S, Gadre, Madhura K, Rider, David N, Liebow, Mark, Goode, Ellen L
Format:	Artigo
Language:	Inglês
Published:	2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2786310/ https://ncbi.nlm.nih.gov/pubmed/18381459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5165
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Genetic variation in the one carbon transfer pathway and ovarian cancer risk

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