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Low Aerobic Capacity and High-Fat Diet Contribute to Oxidative Stress and IRS-1 Degradation in the Kidney
BACKGROUND/AIMS: Insulin receptor (IR-α and IR-β) is reduced in the kidney of insulin-resistant rodents. It is unknown if there are also reductions in insulin receptor substrate (IRS)-1 or if these effects are due to metabolic injury. Thereby, we hypothesized intrinsically high aerobic fitness would...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
S. Karger AG
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786026/ https://ncbi.nlm.nih.gov/pubmed/19229113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000204362 |
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