Treatment of Established Peritoneal Fibrosis by Gene Transfer of Smad7 in a Rat Model of Peritoneal Dialysis

BACKGROUND/AIMS: It has been shown that blockade of TGF-β1 signaling with Smad7 prevents experimental peritoneal fibrosis. The present study investigated whether Smad7 has a therapeutic effect on established peritoneal fibrosis associated with peritoneal dialysis (PD). METHODS: A rat model of perito...

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Bibliographische Detailangaben
Hauptverfasser: Sun, Yanyan, Zhu, Fengxin, Yu, Xueqing, Nie, Jing, Huang, Fengxian, Li, Xiaoyan, Luo, Ning, Lan, Hui Yao, Wang, Yongtao
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2009
Schlagworte:
Original Report: Laboratory Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786025/
https://ncbi.nlm.nih.gov/pubmed/19223683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000203362
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