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Limited Efficacy and Unacceptable Toxicity of Cyclophosphamide for the Induction of Mixed Chimerism and Renal Allograft Tolerance in Cynomolgus Monkeys

To induce mixed chimerism and renal allograft tolerance in cynomolgus monkeys, cyclophosphamide (CP) and total body irradiation (TBI) were compared as part of a nonmyeloablative conditioning regimen. CP induced dose-dependent neutropenia and lymphopenia, but hematopoietic recovery was more rapid tha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sogawa, Hiroshi, Boskovic, Svjetlan, Nadazdin, Ognjenka, Abrahamian, Greg, Colvin, Robert B., Sachs, David H., Cosimi, A. Benedict, Kawai, Tatsuo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786005/
https://ncbi.nlm.nih.gov/pubmed/18724233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181821bac
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