Oral direct thrombin inhibitor AZD0837 for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: a randomized dose-guiding, safety, and tolerability study of four doses of AZD0837 vs. vitamin K antagonists

AIMS: Oral anticoagulation with vitamin K antagonists (VKAs) for stroke prevention in atrial fibrillation (AF) is effective but has significant limitations. AZD0837, a new oral anticoagulant, is a prodrug converted to a selective and reversible direct thrombin inhibitor (AR-H067637). We report from...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lip, Gregory Y.H., Rasmussen, Lars H., Olsson, S. Bertil, Jensen, Eva C., Persson, Anders L., Eriksson, Ulf, Wåhlander, Karin F.C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785945/
https://ncbi.nlm.nih.gov/pubmed/19690349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehp318
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados